Ib qho sib piv ntawm Ob Hom Kev Tiv Thaiv Kev Tiv Thaiv Tus Kheej
Cov tshuaj tua kab mob Monoamine oxidase (MAOIs) raug txiav txim siab yog cov kab mob siab tua kab mob siab tshaj plaws hauv cov kws kho mob hauv tsev kho mob. Lawv ua hauj lwm los ntawm inhibiting qhov enzyme monoamine oxidase hauv lub hlwb.
Xaiv cov xim serotonin rov ua dua ( SSRIs ), ntawm lwm qhov, siv los kho kev nyuaj siab ntxiv rau ntau yam kev txhawj xeeb txog kev ntxhov siab, nrog rau kev tsis sib haum xeeb (PD).
Lawv ua hauj lwm los ntawm inhibiting lub reuptake ntawm serotonin nyob rau hauv lub hlwb, ua rau kev nce ntawm serotonin .
Yuav ua li cas MAOIs Ua Hauj Lwm?
Nws ntseeg hais tias lub hlwb muaj ntau pua hom ntau hom tshuaj xa tuaj (neurotransmitters) uas ua raws li cov neeg sawv cev ntawm cov hlwb sib txawv. Cov tshuaj xaib no yog molecular tshuaj uas tuaj yeem ua rau muaj kev xav, kev ntshaw, kev ntxhov siab, kev pw tsaug zog, lub plawv dhia, qhov kub, kev chim, kev ntshai, thiab lwm yam kev xav ntawm lub hlwb thiab lub cev.
Monoamine oxidase (MAO) yog ib qho enzyme uas ua rau me nyuam lossis ua rau peb cov neurotransmitters nrog rau kev xav thiab ntxhov siab: serotonin, norepinephrine , thiab dopamine . MAOIs txo cov kev ua ntawm lub enzyme MAO, uas ua rau ntau dua ntawm cov kev qhia tsis pub nhiav, serotonin, thiab dopamine hauv lub hlwb. Qhov no, nyeg, ua rau kom zoo siab tuaj thiab muaj kev cuam tshuam los tiv thaiv kev ntshai.
Cov txiaj ntsim ntawm cov kev nce no nce zoo siab tuaj thiab muaj kev cuam tshuam los tiv thaiv cov teeb meem.
Ua li cas SSRIs Ua Haujlwm?
Serotonin yog ib tug neurotransmitter uas yog ib qho tseem ceeb hauv kev hloov ntawm ntau lub cev thiab kev xav, nrog rau peb cov kev xav. Cov kab mob serotonin tsawg tsawg tau txuas rau kev nyuaj siab thiab ntxhov siab . Raws li lub npe siv, SSRIs inhibit rov qab los ntawm serotonin nyob rau hauv lub hlwb. Qhov no ua rau kev nce ntawm serotonin nyob rau hauv ib cheeb tsam ntawm lub paj hlwb hu ua synaptic cleft, uas yog qhov chaw me me ntawm lub hlwb hlwb.
Yog MAOIs Siv Tau Zoo Tshaj, Vim Li Cas SSRIs Feem Ntau Tshaj Tawm?
SSRIs feem ntau yog thawj qhov kev xaiv rau kev kho mob ntawm kev nyuaj siab vim, dhau ntawm qhov ua tau zoo, lawv muaj teeb meem tsawg dua nrog kev mob tshwm sim. Vim tias cov kev txwv tsis pub noj haus thiab kev txhawj xeeb tshaj hypertensive tshua, MAOIs feem ntau siv tom qab lwm tus neeg ua hauj lwm tau ua tsis tiav.
Lwm cov kev mob tshwm sim ntawm MAOIs muaj xws li:
- Txo kev pw tsaug zog / tsis txaus ntsig
- Xeev
- Zawv plab
- Qhov ncauj qhuav
- Kub siab (ntshav siab)
- Hypotension (tsis tshua muaj ntshav siab)
- Kauj taub hau
- Qhov hnyav nce
- Edema (dej tuav)
- Kev sib deev tsis sib deev
- Mob leeg
- Tsis muaj zog
- Tsis meej pem
Ib qho ntawm cov attractions ntawm SSRIs yog tias lawv ntseeg tias yuav muaj kev nyab xeeb thiab tsim muaj cov kev phom sij tsawg dua lwm yam kev kawm ntawm cov tshuaj tiv thaiv kev noj qab haus huv. Tab sis cov tshuaj noj yuav ua rau muaj kev phiv, tshwj xeeb tshaj yog thaum pib kho. Qee cov kev mob tshwm sim ntawm SSRIs muaj xws li:
- Xeev
- Kev sib deev tsis nrog kev sib deev, nrog rau kev muaj siab txaus los yog muaj teeb meem orgasm
- Mob taub hau
- Lub plab chim siab
- Nervousness
- Qhov hnyav nce
- Kev tsaug zog
- Insomnia
Qee qhov kev mob tshwm sim no yuav raug muab tshem tawm tom qab koj lub cev kho rau cov tshuaj. Yog tias lawv tsis ua thiab yog ob leeg, koj tus kws kho mob yuav sim lwm SSRI. Txawm hais tias SSRIs los ntawm ib hom kev ua haujlwm zoo sib xws, lawv txawv.
Qee qhov kev phiv nrog ib tus SSRI yuav tsis yog ib qho teeb meem nrog lwm tus.
Feem ntau, cov kws kho mob yuav tsum tsis txhob sau MAOIs tshwj tsis yog lawv tau ntsib nrog cov tshuaj no.
Ntxiv txog Antidepressants
Cov tshuaj Monoamine Oxidase (MAOIs) . MAOIs yog ib chav kawm ntawm cov tshuaj tua kab mob antidepressants uas tau tsim hauv xyoo 1950. Lawv ua haujlwm zoo rau kev kho tus mob kev nyuab siab, tsis pom kev ntshai, thiab lwm yam kev ntxhov siab. Txawm hais tias lawv feem ntau zoo npaum li SSRIs thiab tricyclic antidepressants (TCAs), lawv siv tsawg vim kev noj haus cov kev tiv thaiv noj haus thiab kev pheej hmoo ntawm kev phiv tshuaj thaum sib xyaw nrog qee cov tshuaj.
Cov tshuaj Monoamine Oxidase (MAOIs) . Cov lus qhia ntxiv txog kev txwv cov kev noj haus, tshuaj yeeb dej caw, thiab lwm cov kev mob tshwm sim.
Kev Xaiv Tsa Tshuaj Txhuam Kom Zoo (Serotonin Reuptake Inhibitors) (SSRIs) . Xav paub ntxiv txog kev noj tshuaj antidepressant / anti-ntxhov siab.