Cov tsos mob ntawm ntau hom kab mob Serotonin
Cov tshuaj tua kab mob hu ua selective serotonin reuptake inhibitors (SSRIs) yog xav kom yog thawj cov kabmob hauv kev kho kabmob ntshai thiab lwm yam kev ntxhov siab . SSRs nce qib ntawm serotonin nyob rau hauv lub hlwb, ua rau muaj kev ntxhov siab vim tsawg thiab inhibition ntawm panic tuaj. Tus neeg yuav xav tias muaj calmer los ntawm cov kab mob serotonin, muaj tsawg dua thiab tsis tshua muaj ceeb ntshai.
Tab sis, yog tias serotonin qib ntau zuj zus tuaj, ib qho mob loj heev hu ua serotonin syndrome yuav ua rau.
Cov tib neeg lub hlwb ntseeg tias muaj kev ua haujlwm hauv cov chaw ua haujlwm ntawm ntau hom neurons thiab neurotransmitters . Neurons yog lub hlwb hlwb, numbering hauv billions, uas muaj peev xwm ntawm kev sib txuas lus sib txuas nrog txhua lwm yam los ntawm chemical txib hu ua neurotransmitters. Serotonin yog ib hom kev xa tshuaj no. Nws plays lub luag haujlwm ntawm kev txhawj xeeb, kev xav, kev pw tsaug zog, kev ntshaw, thiab kev sib deev. Serotonin kuj tsim nyob rau hauv cov hnyuv, ua si lub luag hauj lwm hauv plab zom mov thiab lwm qhov ntawm lub cev tsis muaj dab tsi.
Txheeb xyuas
Serotonin syndrome, los yog serotonin toxicity, yog ib qho tsis tshua muaj tshwm sim los ntawm kev mob siab nyob rau hauv serotonin siab nyob rau hauv lub hlwb. Nws tuaj yeem yog txoj sia yuav tsim kev phem. Feem ntau yog los ntawm kev sib tov ob los sis ntau dua cov tshuaj uas ua rau muaj serotonin theem hauv lub hlwb.
SSRIs, SNRIs , tricyclic antidepressants , MAOIs , thiab triptans yog tag nrho cov kev kawm ntawm cov tshuaj uas tau raug muab siv rau hauv kev txhim kho kev mob serotonin syndrome. Cov antidepressants no feem ntau tau hais kom kho kev nyuaj siab thiab kev ntxhov siab, nrog rau kev tsis sib haum xeeb.
Cov Cim Qhia thiab Cov Tshwm Sim
Cov cim qhia thiab cov tsos mob ntawm serotonin syndrome muaj xws li:
- Tsis meej pem
- Tsis muaj kev sib koom tes
- Nqaij rigidity
- Nyob tsis tswm
- Kev hnov kev pom
- Kev ntxhov siab heev
- Fluctuations nyob rau hauv cov ntshav siab
- Lub plawv dhia plawv
- Xeev, ntuav, raws plab
- Ua npaws
- Tsaus muag
- Coma
Kev kho mob
Txij thaum serotonin syndrome tuaj yeem ua rau lub neej phom sij, kev kho mob kub ceev yog tsim nyog. Kev kho mob pib nrog kev tshem ntawm cov tshuaj causative. Qhov teebmeem ntawm kev mob rau serotonin syndrome yuav ua rau abate hauv 24 mus rau 48 teev tom qab cov tshuaj ua rau serotonin raug nres. Txawm li cas los xij, qee qhov teeb meem xws li delirium thiab tsis muaj zog ntawm lub plawv dhia, ntshav siab, qhov sov thiab lwm yam dej num ntawm lub cev tsis paub qab hau yuav muaj ntev dua. Cov kev pab txhawb thiab kev pabcuam hauv tsev khomob yuav tsim nyog thiab muaj xws li:
Lub plawv dhia thiab kev tswj ntshav siab: Cov tshuaj kom txo tau cov plawv dhia thiab ntshav siab (piv txwv li, esmolol lossis nitroprusside) kuj yuav tsum muaj. Cov tshuaj kuj yuav muab tau yog tias ntshav siab tsawg dhau.
Kev tswj kom sov: Tej zaum nws yuav tsum tau kho cov tsos mob kub taub hau nrog cov pam vov thiab cov txaj hauv txaj txaj.
Sedation: Benzodiazepines yuav siv los tswj kev tswj cov nqaij rigidity thiab kev ntxhov siab heev.
Kua dej: Cov kua hauv cov kua hluav taws xob yuav tsum tau los daws cov dej haus.
Cyproheptadine: Qee zaus siv los thaiv serotonin ntau lawm hauv lub cev. Nws tau ua rau pom kev zoo hauv kev txo cov kev mob ntawm cov tsos mob ntawm serotonin syndrome.
Tiv Thaiv
- Qhia rau koj tus kws kho mob txog txhua yam tshuaj koj tab tom noj. Qhov no suav nrog cov tshuaj kws kho mob, cov tshuaj yuav tom khw, thiab tshuaj noj.
- Yog tias koj noj cov tshuaj uas muaj feem xyuam rau serotonin ntau ntau, nrog koj tus kws kho mob tham txog koj cov kev pheej hmoo rau kev tsim cov kab mob serotonin.
- Nrhiav kev kho mob tam sim ntawd yog tias koj noj cov tshuaj uas muaj feem xyuam rau serotonin ntau ntau thiab koj tsim muaj cov tsos mob ntawm tus kab mob serotonin syndrome.
Qhov chaw:
> Prator, Bettina C. "Serotonin Syndrome." Phau ntawv Journal of Neuroscience Nursing . Lub Plaub Hlis 2006. 38 (2): 102-105.
> US Food and Drug Administration. Muaj Feem Xyuam-Ua Phem rau Serotonin Syndrome nrog kev siv SSRIs los yog SNRIs thiab Triptan Medications. Lub Xya Hli 19, 2006.