FDA Cov Lus Qhia Txog Tej Teebmeem Phem thiab Cov Yim Hli
Nefazodone yog antidepressant uas yuav pab tau cov neeg uas tsis tau zoo rau lwm tus siab phem. Nws ua tau muaj tsawg tsawg, tab sis loj heev, yuav muaj kev puas siab ntsws yog li yuav tsum tau siv kom zoo.
Txheeb xyuas
Cia peb kawm paub ntxiv txog nefazodone, nrog rau cov lus ceeb toom dub, cov teebmeem, thiab cov tshuaj raws li cov lus qhia los ntawm FDA.
Nws tseem ceeb heev uas yuav tsum nco ntsoov hais tias qhov muag ntawm Serzone, lub hom tshuaj ntawm Nefazodone, raug txiav tawm hauv 2003 hauv Tebchaws Meskas vim muaj qhov tsis zoo tshwm sim ntawm daim siab mob siab.
Tab sis generic formulations ntawm nefazodone tseem muaj.
Cov Kev Ua Phem Tsis Txaus Siab
Nyob rau qee zaus, cov neeg uas noj cov tshuaj nefazodone tau tsim txoj sia tsis ua haujlwm. Yog tias koj pom cov tsos mob nram no, hu koj tus kws kho mob tam sim ntawd:
- Yellowing ntawm daim tawv nqaij los yog dawb ntawm lub qhov muag (daj ntseg)
- Zis tsis muaj zis dub
- Tsis qab los noj mov uas kav li ntawm ob peb hnub lossis ntev dua
- Xeev
- Mob plab (plab hauv plab) mob
- Luag tsis zoo
Cov neeg uas twb muaj kab mob hauv siab lawm yuav tsum tsis txhob noj cov tshuaj no.
Cov kws kho mob yuav soj ntsuam xyuas koj lub plab ntshav kuaj ntshav thaum koj noj cov tshuaj nfazodone.
Kev Tua Yus Tus Kheej dub Ceeb Toom
Ib yam li tag nrho cov tshuaj antidepressants, hauv Teb Chaws Asmeskas, nefazodone thau lub npov dub lub ceeb toom txog kev tua neeg. Cov kws kho mob sau cov tshuaj no yog qhia kom lawv saib xyuas lawv cov neeg mob kom lawv kev nyuaj siab los yog kev xav phem, tshwj xeeb yog thaum pib noj tshuaj, lossis thaum twg muaj kev hloov hauv cov tshuaj.
Dosage
Raws li FDA, qhov chaw tsim tshuaj paus kev pom zoo pib yog 200 mg / hnub ob zaug, sawv ntxov thiab yav tsaus ntuj. Qee zaus yuav maj mam nce ntxiv, tos cov kev mob tshwm sim los mus ua ntej mus txog qib tshiab. Hauv kev soj ntsuam, qhov kev siv tshuaj zoo npaum li tau yog 300 mus rau 600 mg / hnub.
Qee qhov kev txhim kho, tshwj xeeb yog thaum ntxhov siab thiab pw tsis tsaug zog (yog tam sim no), yuav tsum tau muaj los ntawm tus neeg mob hauv thawj lub lim tiam los yog ob. Tab sis nws muaj ob peb lub lis piam mus rau ob peb lub hlis rau tag nrho cov kev pab ntawm nefazodone yuav tsum tau ntsib.
Tshuaj Kev Sib Thoob
Nrog koj tus kws kho mob tham ua ntej koj noj cov tshuaj dej nefazodone yog tias koj tseem noj cov tshuaj nram qab no, vim tias muaj kev sib tshuam loj heev tuaj yeem tshwm sim:
- Tegretol (carbamazepine) - feem ntau sau ua ib tus cwj pwm tsis zoo rau kev puas siab puas ntsws bipolar
- Hismanal (astemizole) - kev noj tshuaj tsis haum - tam sim no tawm ntawm kev ua lag luam
- Orap (pimozide) - ib qho tshuaj tiv thaiv kev puas hlwb
- Propulsid (cisapride) - ib qho tshuaj rau cov kab mob kua qaub
- Tej yam tshuaj tua kabmob MAOI
- Halcion (triazolam) - tshuaj tiv thaiv kev ntxhov siab
- Xanax (alprazolam) - tshuaj tiv thaiv kev ntxhov siab
Pub ob lub lim tiam ntawm kev siv tshuaj tiv thaiv MAOI thiab pib nefazodone, thiab ib lim piam nruab nrab ntawm kev txiav ntxiv nefazodone thiab pib kho nrog ib qho MAOI.
Muaj ntau ntau lwm cov kev sib tshuam siv tshuaj nrog nefazodone, yog li nyeem cov lus qhia txog tus neeg mob nrog koj cov tshuaj kom tiav. Qhia rau koj tus kws kho mob yog tias koj pom tej yam teeb meem tshwm sim.
Tsis tas li ntawd, qhov chaw tsim tshuaj yuav tsum qhia cov neeg mob qhia rau lawv tus kws kho mob yog tias lawv cev xeeb tub los yog npaj plab me nyuam thaum noj tshuaj.
Cov neeg mob yuav tsum tiv tauj lawv tus kws kho mob yog tias lawv pub mis niam.
Tej Teebmeem
Nefazodone ua hauj lwm los ntawm kev tiv thaiv kev rov ntsuam xyuas ntawm serotonin thiab norepinephrine , uas yog cov hlwb tshuaj uas cuam tshuam nrog kev nyuaj siab. Txawm li cas los, tsis zoo li SSRI antidepressants, nefazodone txuam nrog tsawg hnyav nce thiab tsawg phiv cov kev phais.
Tsis tas li ntawd, qhov kev ua kom paub txog mania / hypomania kuj yuav qis dua nrog cov roj ntsha muaj zog dua li nrog lwm cov tshuaj antidepressants hauv cov neeg mob bipolar. Uas tau hais tias, qee qhov kev pheej hmoo yuav tsum, yog li cov neeg mob yuav tsum tau saib xyuas los ntawm lawv tus kws kho mob rau qhov pib ntawm mania los yog hypomania thaum noj qhov no lossis cov antidepressant.
Feem ntau cov kev mob tshwm sim muaj xws li:
- tsaug zog
- qhov ncauj qhuav
- xeev siab
- cem quav
- tsis muaj zog
- kiv taub hau
- teeb meem nrog lub zeem muag
- lightheadedness
- tsis meej pem
Kuv Yuav Ua Li Cas?
Yog tias koj tus kws kho mob xav tau kev tso siab rau koj tus kheej kev nyuab siab, nco ntsoov koj rov qab mus nrog nws zoo.
Cov chaw
Carvajal García-Pando A. Hepatotoxicity nrog cov kab mob tshiab antidepressants. J Clin Psychiatry . 2002 Feb; 63 (2): 135-7.
FDA. (2003). Serzone (nefazodonen hydrochloride).