Dub Cov Lus Ceebtoom rau Cov Ntsuj Plig Dawb Hle Clo
Clozaril (clozapine) yog ib qho tshuaj tiv thaiv mob hlwb uas tau pom zoo los siv rau kev siv tshuaj tua tus kab mob schizophrenia thiab kom txo tau txoj kev pheej yig ntawm tus cwj pwm phem rov qab rau cov neeg mob schizophrenia lossis schizoaffective disorder uas raug txiav txim siab tias yuav muaj kev pheej hmoo rau kev hloov rov mus tua tus kheej, keeb kwm thiab tsis ntev los no.
Lus Ceeb Toom Tseem Ceeb rau Clozaril (Clozapine)
Clozaril muaj tsib lus ceeb toom loj heev , hu ua lus ceeb toom dub, txog kev mob tshwm sim los ntawm kev phom sij thiab kev siv yeeb tshuaj. Vim tias cov lus ceeb toom no, Clozaril tsuas yog siv los ntawm qhov kev pab cuam tshwj xeeb uas tswj kev faib cov lus hu ua Clozapine Risk Assessment and Mitigation Strategies (REMS) Program. Ob tus kws kho mob thiab koj tus kws muag tshuaj yuav tsum tau sau npe nrog qhov kev pab cuam no uas cov neeg lag luam tsim los xwv kom muab cov tshuaj Clozaril faib tawm. REMS qhov kev pab cuam saib xyuas kev saib xyuas WBC suav thiab ANC raws li lub sijhawm teev tseg hauv qab no ua ntej xa dej ntawm cov tshuaj tom ntej.
Agranulocytosis
Agranulocytosis yog cov qe ntshav dawb uas tsis txawv txav. Vim cov qe ntshav dawb yog tsim nyog los tua cov kab mob, qhov no yog qhov tshwm sim muaj kev phom sij. Tsawg dua li 1 feem pua ntawm cov neeg mob uas siv cov tshuaj Clozaril yuav tsim muaj agranulocytosis, uas muaj feem cuam tshuam rau lub neej tsis zoo.
Yog tias koj raug kho nrog clozapine, koj yuav tsum muaj cov ntshav dawb (WBC) suav thiab suav neutrophil suav (ANC) ua ntej koj tuaj yeem pib Clozaril, nrog rau WBC suav nrog thiab ANCs thaum kho thiab tsawg kawg 4 lub lis piam tom qab txiav kev kho mob.
Txoj Kev Txom Nyem
Qaug dab peg tau txuam nrog kev siv clozapine.
Dose zoo nkaus li yog ib qho tseem ceeb ntawm kev qaug dab peg, nrog ntau dua ntawm cov tshuaj clozapine ntau dua. Kev ceeb toom yuav tsum tau siv thaum siv cov tshuaj clozapine rau cov neeg mob uas muaj keeb kwm ntawm qaug dab peg lossis lwm yam cuam tshuam. Cov neeg mob yuav tsum raug qhia kom tsis txhob koom tes hauv ib qho dej num twg qhov kev poob siab tsis paub yuav ua teeb meem loj rau lawv tus kheej lossis lwm tus.
Myocarditis thiab Cardiomyopathy
Myocarditis yog mob ntawm lub plawv mob thiab cardiomyopathy yog ib lub plawv mob siab. Yog tias koj ua tsis taus pa, ua npaws, qaug zog lossis mob hauv siab thaum noj cov tshuaj Clozaril, nco ntsoov hu koj tus kws kho mob tam sim ntawd.
Lwm yam kev mob ntsws thiab kab mob ntsws
Orthostatic hypotension yog ib qho loj, cia li txo qis hauv siab raws li qhov uas ua rau koj xav tias lightheaded los yog daub. Syncope txhais tau tias tsaus muag.
Orthostatic hypotension, nrog lossis tsis muaj syncope, tuaj yeem tshwm sim nrog kev kho mob clozapine, tshwj xeeb tshaj yog thaum koj pib noj nws los yog koj cov tshuaj hloov lawm. Tsis tshua muaj qhov no, qhov no tuaj yeem ua rau: thiab muaj kev sib ntswg thiab / los yog plawv nres. Yog tias koj muaj mob raws plab lossis ntuav lossis lwm yam tshwm sim ntawm lub cev qhuav dej, nco ntsoov qhia koj tus kws kho mob. Tsis tas li ntawd, yog tias koj hla dhau ob zaug los yog ntau zaug ntawm Clozaril, nrog koj tus kws kho mob tham ua ntej koj noj koj cov tshuaj ntxiv tom qab koj tuaj yeem siv tshuaj dua ib zaug.
Muaj Cov Txij Ntsig hauv Cov Laus Cov Teeb Meem Nrog Dementia
Cov neeg mob laus uas muaj kev xav txog kev mob ntshav ntsws dementia nrog tshuaj atypical antipsychotic yog cov kev pheej hmoo ntawm kev tuag piv rau cov placebo . Hauv ib txoj kev tshawb nrhiav, txawm hais tias qhov ua rau muaj kev ploj tuag ntau, feem ntau ntawm cov neeg tuag tau tshwm sim los ntawm kev mob plawv, lawv txhais tau hais txog kev mob plawv los yog kev tuag sai, los yog kev kis mob. Clozaril tsis tau txais kev pom zoo rau kev kho mob ntawm cov neeg mob uas muaj kev nyuab siab ntsig txog kev mob hlwb.
Qhov chaw:
"Clozapine (Clozaril / FazaClo)." National Alliance ntawm Kev Mob Hlwb (2014).
"Clozapine." MedLine Plus, Tebchaws Asmeskas Lub Tsev Qiv Ntawv Tshuaj Kho Mob (2015).