Tshuaj Tus Neeg Siv Lub Ntsws Kev Puas Hlwb Tau Pom Zoo rau Thaum Ntxov Txog Hnub Nyoog 17
Cov kev soj ntsuam ntawm postmortem ntawm 34 cov tub ntxhais hluas uas hmoov tsis tuag thaum muaj hnub nyoog yau tau muab cov kws tshawb fawb pom ib qho tsis zoo rau kev puas tsuaj uas siv cov tshuaj txhaj tshuaj ua rau lub hlwb ntawm cov neeg siv.
Nyob rau hauv kev tshawb fawb tawm hauv Neuropathology thiab Applied Neurobiology, cov neeg tshawb xyuas soj ntsuam cov paj hlwb 34 thiab tus neeg siv tshuaj methadone uas tau tuag thaum muaj hnub nyoog 26 xyoo.
Ib txhia ntawm lawv tuag nyob rau hauv 17. Lawv piv lawv lub hlwb rau lub hlwb ntawm 16 cov tub ntxhais hluas uas tuag lub hnub nyoog tab sis tsis siv tshuaj yaj yeeb.
Kev kuaj pom tau tias cov neeg quav tshuaj yeeb tau siv li ntawm peb zaug ntau dua uas yuav muaj hlwb puas tsuaj dua li cov neeg uas tsis siv yeeb tshuaj. Cov neeg siv yeeb tshuaj rau cov tub ntxhais hluas lub paj hlwb zoo ib yam li cov neeg laus thiab cov kev puas tsuaj rau cov neeg muaj mob Alzheimer's disease.
Hlwb Mob Hlwb Hauv Cov Neeg Siv Tshuaj
Cov kws tshawb fawb hauv University of Edinburgh tau tshawb cov hlwb ntawm cov neeg tua tshuaj tua kabmob ntawm heroin thiab methadone thiab muab piv rau cov paj hlwb ntawm cov neeg hluas uas tsis siv yeeb tshuaj.
Cov hlab ntsha uas raug puas tsuaj tau nyob hauv cov cheeb tsam ntawm lub hlwb tau koom hauv kev kawm, nco, thiab kev xav zoo, thiab zoo li kev puas tsuaj pom nyob rau hauv cov theem thaum ntxov ntawm Alzheimer's tus kab mob.
"Peb cov kev tshawb fawb qhia tau tias muaj kev pheej hmoo ntawm lub hlwb puas tsuaj nrog heroin thiab methadone, uas tej zaum yuav siab tshaj rau cov hluas thaum tib neeg xav tau qhov cuj pwm," said co-author Jeanne Bell xib fwb ntawm Neuropathology.
"Peb pom hais tias lub hlwb ntawm cov tshuaj yaj yeeb ntawm cov tub ntxhais hluas cov yeeb tshuaj tau pom muaj ntau dua ob lub ntsiab lus tseem ceeb nrog cov hlwb puas."
"Nyob hauv kev tshawb nrhiav yav dhau los, peb pom tias kev quav yeeb tshuaj ua rau muaj mob tsawg tsawg rau hauv lub hlwb." Ua ke, ob txoj kev tshawb fawb qhia tias kev siv yeeb tshuaj tiv thaiv kev sib deev txuas rau txuas mus thaum ntxov ntawm lub hlwb, "Bell said.
Heroin thiab tshuaj txiav yeeb (Methadone Cause Damage)
Qhov nruab nrab hnub nyoog hauv ob pawg no hauv txoj kev tshawb no tau tsuas yog 26 xyoos thiab muaj qee tus neeg ua phem siv tshuaj yeeb thaum muaj hnub nyoog 17 xyoo.
"Tau protein, uas nyob rau hauv nws daim ntawv daws teeb meem yog qhov tseem ceeb rau kev sib txuas lus thiab kev thauj hauv hlwb hlwb, tau ua tsis muaj nyob hauv qee tus hlwb, ua rau lub paj hlwb raug mob thiab tuag hauv cov cheeb tsam ntawm lub hlwb," tus sau phau ntawv qhia. "Lwm cov paj hlwb pom muaj kev txuam ntawm cov thooj av amyloid precursor, uas qhia tias cov khoom thauj thauj tau cuam tshuam thiab cov paj hlwb cov cuam tshuam cuam tshuam."
Mob Hnyiab Mob Hlwb
"Qhov kev tshawb nrhiav no qhia tau tias kev tsim txom cov tshuaj muaj peev xwm ua rau muaj cov kabmob ua rau muaj kev puas hlwb thiab tuag hauv qhov tseemceeb ntawm lub hlwb." Qhov no yog kev txhawj xeeb vim tias muaj cov yeeb-tshuaj uas siv cov tshuaj phem, tshwj xeeb tshaj yog opiates xws li tus nees ej thiab methadone, tau nce ntxiv nyob rau hauv xyoo tas los , "hais tias Professor Bell.
"Cov neeg quav yeeb tshuaj uas peb saib nyob rau hauv txoj kev tshawb no tu siab thaum ib tug me nyuam hluas, tab sis muaj ntau lwm tus neeg uas tsis paub txog cov kev nyuab siab ntev uas cov tshuaj yuav ua ntawd."