Wellbutrin - kuj paub los ntawm nws lub npe hu ua, bupropion - yog antidepressant uas yog qee zaum siv los kho kev nyuaj siab rau kev puas siab puas ntsws bipolar. Bupropion lub chaw muag khoom muag cov tshuaj nyob rau hauv peb lub npe, zoo li: Zyban, ib qho tshuaj muag kev lag luam los pab tib neeg txiav luam yeeb.
Cov tshuaj no muaj tso tawm sai sai (75 thiab 100 mg ntsiav tshuaj) thiab tso tawm (100 thiab 150 mg) qauv (muag li Wellbutrin SR®).
Nws tsis pom tseeb tias vim li cas Wellbutrin ua haujlwm kom txo cov kev mob tshwm sim . Chemically, nws tsis yog ntsig txog lwm yam tshuaj tiv thaiv kab mob loj. Txawm li cas los xij, kev tshawb fawb pom tias nws ua hauj lwm, thiab nws yuav muaj kev zoo dua lwm cov tshuaj tiv thaiv kev nyuaj siab rau kev kho kev nyuaj siab rau cov tib neeg muaj kev puas siab puas ntsws bipolar.
Wellbutrin nyob rau hauv kev puas siab puas ntsws Bipolar
Cov tshuaj tua kab mob (Antidepressants) , nrog rau Wellbutrin, tau siv cov teeb meem hauv kev puas siab puas ntsws bipolar, txawm tias tsis muaj pov thawj ntau rau lawv txoj kev nyab xeeb thiab kev pab. Tsawg tau tsim cov kev tshawb fawb txog kev kho mob ntev ntev, thiab nws tsis meej meej tias cov tshuaj antidepressants yuav ua li cas nrog cov cwj pwm tsis txaus siab rau cov neeg uas muaj kev puas siab puas ntsws bipolar.
Muaj 10-lub lim piam kev kawm tau qhia tias Wellbutrin tau pab txog ib nrab ntawm cov neeg uas muaj kev puas siab puas ntsws bipolar uas tau txais kev kho mob nrog rau cov tshuaj thaum lawv tseem noj cov neeg nyob siab.
Thaum sau cov tshuaj tua kab mob antidepressants rau lawv cov neeg mob bipolar, cov psychiatrists mas feem ntau txhawj xeeb txog "kev hloov siab kaj siab," uas yog thaum muaj kev ntxhov siab sai sai rau kev tswjhwm, mob plab hnyuv lossis lub xeev sib xyaw.
Muaj qee yam ua pov thawj tias Wellbutrin yuav muaj qis dua "kev hloov ntawm cov txiv neej" thaum piv nrog lwm hom antidepressants, xws li cov laus hauv tricyclic antidepressants thiab cov neeg tsis tuaj yeem tso tshuaj tsis tu ncua (SNRIs). Kwv yees li ntawm 10% ntawm cov neeg mob hauv txoj haujlwm 10 lub lim piam tau pom tias lawv cov tsos mob siab heev, piv rau li 29% rau cov neeg SNRI.
Txoj kev hloov siab xav tau tshwm sim ntau dua rau cov neeg uas muaj kev puas siab ntsws bipolar Kuv uas tau noj tshuaj tua kabmob (antidepressants). Yog li ntawd, cov kws qhia tau pom zoo tias cov neeg mob bipolar kuv tsuas tau txais cov tshuaj antidepressants nrog rau cov tshuaj noj tshuaj kom zoo.
Pib Wellbutrin: Cov Txheej Txheem Zog
Koj tus kws kho mob feem ntau yuav xav pib koj ntawm Wellbutrin los yog Zyban ntawm ib qho tshuaj tsawg dua thiab tom qab ntawd ua rau koj noj ntau dua, vim muaj kev phom sij ntawm kev phiv .
Thaum koj xub pib noj Wellbutrin, koj thawj zaug yuav tsum tsis pub tshaj 150 mg / hnub. Qhov no yuav nce ntxiv kom tsis pub tshaj 300 mg / hnub rau hnub plaub uas thaum siv los ntawm kev haus luam yeeb, thiab nws thiaj li 400 mg (tso tawm) lossis 450 mg (tso tawm sai) thaum siv los kho kev nyuaj siab.
Hauv cov tshuaj 400-450 mg / hnub koj yuav muaj qaug dab peg, txawm tias nws tseem heev, tsawg heev: plaub ntawm 1,000 tus neeg raug mob los ntawm Wellbutrin ntawm qhov tshuaj no. Cov neeg mob uas ua rau muaj kev ntxhov siab, nyob tsis tswm los yog insomnia yuav tsum nyob twj ywm ntawm qis dua thiab / los sis ua rau kom qis ntau dua. Nws yuav siv li ntawm 1 mus rau plaub lub lis piam rau cov neeg mob uas siv cov tshuaj pleev kom hnov cov kev pab tas nrho.
Feem ntau cov kev mob tshwm sim ntawm kev siv tshuaj muaj xws li mob taub hau, qhov ncauj qhuav, xeev siab, thiab insomnia.
Txawm hais tias muaj ntau yam tshuaj tiv thaiv antidepressants ua rau los sis ua rau hnyav nce, Wellbutrin / Zyban yog xam qhov "qhov hnyav nruab nrab," thiab ntau tus neeg qhia txog qhov hnyav tshaj qhov muaj nyhav thaum noj cov tshuaj.
Ceev faj txog Wellbutrin / Zyban
Nov yog qee yam uas koj yuav tsum tau saib thaum siv cov tshuaj no:
- Qhov tsawg feem pua ntawm cov neeg tau hnov mob anorexia thaum noj cov tshuaj no, yog li cov neeg mob keeb kwm ntawm kev mob anorexia nervosa los yog bulimia , lossis nrog keeb kwm ntawm qaug dab peg, yuav tsum tsis txhob noj cov tshuaj no. Qhov tseeb, qee qhov kev pom zoo xav tias Bupropion tsis raug coj los ntawm tus neeg uas them tsis taus poob ntau tshaj 5% ntawm lub cev qhov hnyav tam sim no.
- Yog tias koj noj tshuaj tiv thaiv kab mob MAOI, koj yuav tsum tos tsawg kawg ob lub lim tiam tom qab koj qhov tshuaj tiv thaiv zaum kawg pib Wellbutrin / Zyban.
- Bupropion tsis paub tias muaj kev phom sij thaum cev xeeb tub lossis kev tu mob, tab sis koj tus kws kho mob thiab tus kws kho mob yuav tsum paub txhua yam tshuaj uas koj noj txhua lub sijhawm.
- Yog tias koj ncua kev noj tshuaj, HNUB YUAV. Txoj kev pheej hmoo ntawm qaug dab peg yog koob tshuaj, thiab twv ntxiv yog qhov ua rau qaug dab peg.
- Tsis txhob noj cov dej Wellbutrin THIAB Zyban. Txhua yam koj yuav tau ua yog nce kab ntau ntxiv rau qhov phom sij txaus ntshai.
- Kev siv - tshwj xeeb tshaj yog siv - haus dej cawv ua rau kev pheej hmoo ntawm qaug dab peg thaum noj cov phom sij.
- Kev kho mob yuav tsum tau noj thaum sib txuas nrog Wellbutrin los yog Zyban nrog cov tshuaj anticonvulsant phenytoin (lub npe hu ua Dilantin), carbamazepine (lub npe Tegretol) (uas yog feem ntau siv los kho tus mob bipolar), los yog phenobarbital, los yog nrog cov tshuaj noj cimetidine (lub npe Tagamet ).
Qhov chaw:
National Alliance ntawm Mental Illness. Daim ntawv qhia qhov tseeb ntawm Bupropion (Wellbutrin).
Pacchiarotti kuv li al. Lub Koom Haum Thoob Ntiaj Teb rau Bipolar Disorders (ISBD) qhia tawm tsam txog kev siv antidepressant hauv kev puas siab puas ntsws bipolar. American Journal of Psychiatry. 2013 Nov; 170 (11): 1249-62.
Ncej RM li al. Kev hloov mus ob lub rau kev siab ntsws bipolar: sib piv ntawm venlafaxine adjunctive, bupropion, thiab sertraline. British Journal of Psychiatry. Jul 2006, 189 (2) 124-131.